PAK1,PAK2,PAK3单克隆抗体(DGR19432) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Phospho-PAK1/2/3 (Ser144/Ser141/Ser154) (DGR19432) Rabbit mAb (PBS Only)

db11225-PBS

Datasheet

Product Name : Phospho-PAK1/2/3 (Ser144/Ser141/Ser154) (DGR19432) Rabbit mAb (PBS Only)

Cat.No.: db11225-PBS

Synonyms : PAKalpha

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser144 of human PAK1
Gene ID 5058
Swiss Prot O75914
Synonyms PAKalpha
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:2000-1:20000
IHC-P: 1:100-1:500
ICC/IF: 1:200-1:500
FC: 1:100
IP: 1:20-1:50
Calculated MW 61 kDa
Observed MW 61 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR19432
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of PAK1 (Phospho-Ser144)/PAK2 (Phospho-Ser141)/PAK3 (Phospho-Ser154) in C6,3T3,Hela cell lysates using db11225(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human breast cancer using db11225

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