Phospho-PAK1/2/3 (Ser144/Ser141/Ser154) (DGR19432) Rabbit mAb
Product Name :
Phospho-PAK1/2/3 (Ser144/Ser141/Ser154) (DGR19432) Rabbit mAb
Cat.No.:
db11225
Synonyms :
PAKalpha
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser144 of human PAK1
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Gene ID
5058
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Swiss Prot
O75914
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Synonyms
PAKalpha
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P, ICC/IF, FC, IP
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Recommended dilution
WB: 1:2000-1:20000
IHC-P: 1:100-1:500
ICC/IF: 1:200-1:500
FC: 1:100
IP: 1:20-1:50
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Calculated MW
61 kDa
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Observed MW
61 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR19432
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot detection of PAK1 (Phospho-Ser144)/PAK2 (Phospho-Ser141)/PAK3 (Phospho-Ser154) in C6,3T3,Hela cell lysates using PAK1 (Phospho-Ser144)/PAK2 (Phospho-Ser141)/PAK3 (Phospho-Ser154) antibody(1:1000 diluted).
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Immunohistochemical analysis of paraffin-embedded human breast cancer using db11225 antibody.
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Immunofluorescent analysis of HeLa cells using db11225 antibody (green), and DAPI (blue).
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.