CREB Regulated Transcription Coactivator 2单克隆抗体(DGR31742) | 高特异性&高亲和力

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Recombinant DGRmAb^®

CREB Regulated Transcription Coactivator 2 (DGR31742) Rabbit mAb (PBS Only)

db11256-PBS

Datasheet

Product Name : CREB Regulated Transcription Coactivator 2 (DGR31742) Rabbit mAb (PBS Only)

Cat.No.: db11256-PBS

Synonyms : TORC2; TORC-2

Application：

Reactivity : Human, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]
Immunogen A synthetic peptide of human TORC2
Gene ID 200186
Swiss Prot Q53ET0
Synonyms TORC2; TORC-2
Reactivity Human,Rat
Application WB, IHC-P
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:100-1:200
Calculated MW 73 kDa
Observed MW 80 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR31742
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of TORC2 in A549,HL-60,U251 cell lysates using db11256(1:1000 diluted).
Western blot analysis of extracts from HeLa cells using db11256

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