CREB Regulated Transcription Coactivator 2 (DGR31742) Rabbit mAb
Product Name :
CREB Regulated Transcription Coactivator 2 (DGR31742) Rabbit mAb
Cat.No.:
db11256
Synonyms :
TORC2; TORC-2
Reactivity :
Human, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]
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Immunogen
A synthetic peptide of human TORC2
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Gene ID
200186
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Swiss Prot
Q53ET0
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Synonyms
TORC2; TORC-2
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Reactivity
Human,Rat
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Application
WB, IHC-P
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
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Calculated MW
73 kDa
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Observed MW
80 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR31742
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot detection of TORC2 in A549,HL-60,U251 cell lysates using TORC2 antibody(1:1000 diluted).
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Western blot analysis of extracts from HeLa cells using db11256 at 1:1000.
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Immunohistochemical analysis of paraffin-embedded human breast cancer using db11256 antibody.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.