Phospho-IGF-I receptor beta (Tyr1166)/Insulin receptor beta (Tyr1190)/Insulin receptor-related protein beta (Tyr1146) (DGR14098) Rabbit mAb (PBS Only)
Product Name :
Phospho-IGF-I receptor beta (Tyr1166)/Insulin receptor beta (Tyr1190)/Insulin receptor-related protein beta (Tyr1146) (DGR14098) Rabbit mAb (PBS Only)
Cat.No.:
db11281-PBS
Synonyms :
IGFR; CD221; IGFIR; JTK13
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Tyr1166 of IGF-I receptor beta/Insulin receptor beta/Insulin receptor-related protein beta
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Gene ID
3480
3643
3645
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Swiss Prot
P08069
P08069
P14616
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Synonyms
IGFR; CD221; IGFIR; JTK13
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Reactivity
Human,Mouse,Rat
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Application
WB, IP
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Recommended dilution
WB: 1:1000
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Calculated MW
155 kDa
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Observed MW
95 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR14098
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
4498
- 货期：现货
For research use only. Not intended for diagnostic.
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