Phospho-IGF-I receptor beta (Tyr1166)/Insulin receptor beta (Tyr1190)/Insulin receptor-related protein beta (Tyr1146) (DGR14098) Rabbit mAb
Product Name :
Phospho-IGF-I receptor beta (Tyr1166)/Insulin receptor beta (Tyr1190)/Insulin receptor-related protein beta (Tyr1146) (DGR14098) Rabbit mAb
Cat.No.:
db11281
Synonyms :
IGFR; CD221; IGFIR; JTK13
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
-
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
-
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Tyr1166 of IGF-I receptor beta/Insulin receptor beta/Insulin receptor-related protein beta
-
Gene ID
3480
3643
3645
-
Swiss Prot
P08069
P08069
P14616
-
Synonyms
IGFR; CD221; IGFIR; JTK13
-
Reactivity
Human,Mouse,Rat
-
Application
WB, IP
-
Recommended dilution
WB: 1:1000
-
Calculated MW
155 kDa
-
Observed MW
95 kDa
-
Host species
Rabbit
-
Clonality
Monoclonal
-
Clonality No.
DGR14098
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
-
Package
Price (RMB)
-
10μL
398
-
20μL
698
-
50μL
1398
-
100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
浙公网安备 33010602008812号