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Phospho-IGF1 Receptor (Tyr1166) (DGR14098) Rabbit mAb
db11281
Datasheet
- Background This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R
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Gene ID
3480
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Swiss Prot
P08069
- Synonyms IGFR; CD221; IGFIR; JTK13
- Reactivity Human,Mouse,Rat
- Application WB, IP
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Recommended dilution
WB: 1:2000-1:20000
IP: 1:10-1:100 - Calculated MW 155 kDa
- Observed MW 95 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14098
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Phospho-IGF-1R (Tyr1166) in C6,3T3,Hela cell lysates using Phospho-IGF-1R (Tyr1166) antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
