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STAT6 (DGR14321) Rabbit mAb (PBS Only)
db11282-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- Immunogen A synthetic peptide of human STAT6
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Gene ID
6778
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Swiss Prot
P42226
- Synonyms STAT6B; STAT6C; D12S1644; IL-4-STAT
- Reactivity Human, Mouse, Rat
- Application WB, ICC/IF, IP
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Recommended dilution
WB: 1:1000
ICC/IF: 1:200-1:500
IP: 1:50 - Calculated MW 94 kDa
- Observed MW 110 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14321
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of STAT6 in Jurkat,CHO-K1,Hela cell lysates using db11282(1:500 diluted).
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
