STAT6 (DGR14321) Rabbit mAb
Product Name :
STAT6 (DGR14321) Rabbit mAb
Cat.No.:
db11282
Synonyms :
STAT6B; STAT6C; D12S1644; IL-4-STAT
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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Immunogen
A synthetic peptide of human STAT6
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Gene ID
6778
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Swiss Prot
P42226
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Synonyms
STAT6B; STAT6C; D12S1644; IL-4-STAT
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Reactivity
Human, Mouse, Rat
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Application
WB, ICC/IF, IP
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Recommended dilution
WB: 1:1000
ICC/IF: 1:200-1:500
IP: 1:50
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Calculated MW
94 kDa
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Observed MW
110 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR14321
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot detection of STAT6 in Jurkat,CHO-K1,Hela cell lysates using STAT6 antibody(1:500 diluted).
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.