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Erlin-2 (DGR35916) Rabbit mAb (PBS Only)
db11311-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
- Immunogen A synthetic peptide of human Erlin-2
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Gene ID
11160
244373
-
Swiss Prot
O94905
Q8BFZ9
- Synonyms NET32; SPFH2; SPG18; C8orf2; Erlin-2
- Reactivity Human,Mouse
- Application WB, IHC-P, ICC/IF
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:50-1:100
ICC/IF: 1:100-1:200 - Calculated MW 38 kDa
- Observed MW 43 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR35916
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HepG2 cells using db11311 at 1:1000. -
Immunofluorescence analysis of HeLa cells labelling Erlin-2 with db11311.
The cells were fixed with 4% PFA (10min, RT) followed by treatment with 0.1% Triton X-100 (10min, RT), and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db11311 (1:100) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 (db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.
Control: Secondary antibody only.
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
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For research use only. Not intended for diagnostic.
