FADD (DGR11188) Rabbit mAb (PBS Only)
Product Name :
FADD (DGR11188) Rabbit mAb (PBS Only)
Cat.No.:
db11505-PBS
Synonyms :
Mort1/FADD
Reactivity :
Mouse
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).
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Immunogen
A synthetic peptide of mouse FADD
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Gene ID
14082
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Swiss Prot
Q61160
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Synonyms
Mort1/FADD
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Reactivity
Mouse
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Application
WB, IHC-P, ICC/IF, FC, IP
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Calculated MW
23 kDa
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Observed MW
28 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR11188
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of FADD in SHSY-5Y cell lysates using FADD antibody(1:1000 diluted).
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Immunohistochemical analysis of paraffin-embedded mouse liver using
db11505 antibody.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.