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Rab7 (DGR14373) Rabbit mAb (PBS Only)
db11619-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human RAB7
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Gene ID
7879
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Swiss Prot
P51149
- Synonyms RAB7; PRO2706
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC
- Calculated MW 24 kDa
- Observed MW 24 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14373
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from K562, C6, 3T3, HeLa using db11619 at 1:1000. -
Immunohistochemical analysis of paraffin-embedded mouse colon using db11619 antibody. -
Immunofluorescent analysis of HeLa cells using db11619 antibody (green), and DAPI (blue). -
Immunofluorescence analysis of A549 cells labelling Rab7 with db11619.
The cells were fixed with 4% PFA (10min, RT) followed by treatment with 0.1% Triton X-100 (10min, RT), and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db11619 (1:100) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 (db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.
Control: Secondary antibody only.
订购信息
- Package Price (RMB)
- 10μg 2598
- 100μg 7858
- 货期：现货
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For research use only. Not intended for diagnostic.
