Desmocollin 3 (DGR11800) Rabbit mAb (PBS Only)
Product Name :
Desmocollin 3 (DGR11800) Rabbit mAb (PBS Only)
Cat.No.:
db11817-PBS
Synonyms :
DSC; DSC1; DSC2; DSC4; CDHF3; HT-CP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
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Immunogen
A synthetic peptide of human Desmocollin 3
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Gene ID
1825
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Swiss Prot
Q14574
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Synonyms
DSC; DSC1; DSC2; DSC4; CDHF3; HT-CP
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Reactivity
Human,Mouse,Rat
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Application
WB, FC
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Calculated MW
100 kDa
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Observed MW
100 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR11800
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of Desmocollin 3 in K562,Hela cell lysates using Desmocollin 3 antibody(1:1000 diluted).
订购信息
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Package
Price (RMB)
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10μg
2598
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100μg
7858
- 货期:现货
For research use only. Not intended for diagnostic.