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Conjugation/Formulation：Un-conjugated
- Background The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
- Immunogen A synthetic peptide of human Desmocollin 3
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Gene ID
1825
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Swiss Prot
Q14574
- Synonyms DSC; DSC1; DSC2; DSC4; CDHF3; HT-CP
- Reactivity Human,Mouse,Rat
- Application WB, FC
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Recommended dilution
WB: 1:2000-1:20000
FC: 1:10-1:100 - Calculated MW 100 kDa
- Observed MW 100 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11800
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Desmocollin 3 in K562,Hela cell lysates using Desmocollin 3 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
