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Recombinant DGRmAb®
KCTD21 (DGR15071) Rabbit mAb (PBS Only)
db11964-PBS
Datasheet

Product Name : KCTD21 (DGR15071) Rabbit mAb (PBS Only)

Cat.No.: db11964-PBS

Synonyms : KCASH2

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation：PBS Only

Un-conjugated PBS Only
  • Background Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).
  • Immunogen Recombinant protein of human KCTD21
  • Gene ID 283219
  • Swiss Prot Q4G0X4
  • Synonyms KCASH2
  • Reactivity Human,Mouse,Rat
  • Application WB, FC
  • Calculated MW 30 kDa
  • Observed MW 30 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR15071
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
  • Western blot analysis of extracts from K562 cells using db11964 at 1:1000.
  • Western blot analysis of extracts from Mouse brain, Rat brain tissues using db11964 at 1:1000.
订购信息
  • Package Price (RMB)
  • 100μg 4498
  • 货期：现货
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For research use only. Not intended for diagnostic.