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KCTD21 (DGR15071) Rabbit mAb
db11964
Datasheet
- Background Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).
- Immunogen Recombinant protein of human KCTD21
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Gene ID
283219
-
Swiss Prot
Q4G0X4
- Synonyms KCASH2
- Reactivity Human,Mouse,Rat
- Application WB, FC
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Recommended dilution
WB: 1:1000
FC: 1:100-1:200 - Calculated MW 30 kDa
- Observed MW 30 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15071
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of KCTD21 in K562 cell lysates using KCTD21 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
