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KAT1 (DGR19782) Rabbit mAb (PBS Only)
db12046-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]
- Immunogen Recombinant protein of human KAT1
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Gene ID
8520
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Swiss Prot
O14929
- Synonyms KAT1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC, IP
- Calculated MW 50 kDa
- Observed MW 45 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19782
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from K562, C6, 3T3, and HeLa cells using db12046 at 1:1000. -
Immunohistochemical analysis of paraffin-embedded human tonsil using db12046 antibody. -
Immunofluorescent analysis of HeLa cells using db12046 antibody (green), and DAPI (blue). -
Immunofluorescence analysis of K562 cells labelling KAT1 with db12046.
The cells were fixed with 4% PFA (10min, RT) followed by treatment with 0.1% Triton X-100 (10min, RT), and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db12046 (1:200) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 (db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.
Control: Secondary antibody only.
订购信息
- Package Price (RMB)
- 10μg 1498
- 100μg 4498
- 货期：现货
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For research use only. Not intended for diagnostic.
