Dnmt1单克隆抗体(DGR19467) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Dnmt1 (DGR19467) Rabbit mAb (PBS Only)

db12139-PBS

Datasheet

Product Name : Dnmt1 (DGR19467) Rabbit mAb (PBS Only)

Cat.No.: db12139-PBS

Synonyms : AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; m.HsaI

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Immunogen A synthetic peptide of human Dnmt1
Gene ID 1786
Swiss Prot P26358
Synonyms AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; m.HsaI
Reactivity Human
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
ICC/IF: 1:50-1:100
FC: 1:100-1:1000
IP: 1:20
Calculated MW 183 kDa
Observed MW 183 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR19467
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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