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RAB7 (DGR16231) Rabbit mAb (PBS Only)
db12231-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human RAB7
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Gene ID
7879
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Swiss Prot
P51149
- Synonyms RAB7; PRO2706
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, FC
- Calculated MW 24 kDa
- Observed MW 24 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16231
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from 3T3 cells using db12231 at 1:1000. -
Western blot analysis of extracts from C2C12 cells and Mouse brain tissue using db12231 at 1:1000. -
Immunohistochemical analysis of paraffin-embedded human lung cancer using db12231 antibody. -
Immunofluorescence analysis of HeLa cells labelling RAB7 with db12231.
The cells were fixed with 4% PFA (10min, RT) followed by treatment with 0.1% Triton X-100 (10min, RT), and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db12231 (1:50) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 (db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.
Control: Secondary antibody only.
订购信息
- Package Price (RMB)
- 10μg 1498
- 100μg 4498
- 货期：现货
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For research use only. Not intended for diagnostic.
