CD11b单克隆抗体(DGR11714) | 高特异性&高亲和力

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Recombinant DGRmAb^®

CD11b (DGR11714) Rabbit mAb (PBS Only)

db12238-PBS

Datasheet

Product Name : CD11b (DGR11714) Rabbit mAb (PBS Only)

Cat.No.: db12238-PBS

Synonyms : CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik

Application：

Reactivity : Mouse

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Immunogen A synthetic peptide of mouse CD11b
Gene ID 16409
Swiss Prot P05555
Synonyms CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik
Reactivity Mouse
Application WB, ICC/IF, IP
Calculated MW 128 kDa
Observed MW 170 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR11714
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/mL
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot analysis of extracts from RAW264.7 cells and Rat spleen tissue using db12238 at 1:1000.

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