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DROSHA (DGR33325) Rabbit mAb
db12329
Datasheet
- Background This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]
- Immunogen Recombinant protein of human DROSHA
-
Gene ID
29102
-
Swiss Prot
Q9NRR4
- Synonyms RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976
- Reactivity Human,Mouse,Rat
- Application WB, ICC/IF, FC
-
Recommended dilution
WB: 1:1000
ICC/IF: 1:50
FC: 1:200-1:500 - Calculated MW 159 kDa
- Observed MW 159 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR33325
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
