PUMA (DGR14872) Rabbit mAb (PBS Only)
Product Name :
PUMA (DGR14872) Rabbit mAb (PBS Only)
Cat.No.:
db12341-PBS
Synonyms :
JFY1; PUMA; JFY-1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
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Immunogen
A synthetic peptide of human PUMA
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Gene ID
27113
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Swiss Prot
Q9BXH1
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Synonyms
JFY1; PUMA; JFY-1
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Reactivity
Human
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Application
WB, IHC-P, ICC/IF, FC
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Calculated MW
21 kDa
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Observed MW
21 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR14872
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of PUMA in Jurkat,THP-1,C6,3T3,Hela cell lysates using PUMA antibody(1:1000 diluted).
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Immunohistochemical analysis of paraffin-embedded human breast cancer using
db12341 antibody.
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Immunofluorescent analysis of 293T cells using
db12341 antibody (green), and DAPI (blue).
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.