Cathepsin B单克隆抗体(DGR18146) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Cathepsin B (DGR18146) Rabbit mAb (PBS Only)

db12432-PBS

Datasheet

Product Name : Cathepsin B (DGR18146) Rabbit mAb (PBS Only)

Cat.No.: db12432-PBS

Synonyms : CB

Application：

Reactivity : Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]
Immunogen Recombinant protein of mouse Cathepsin B
Gene ID 13030
Swiss Prot P10605
Synonyms CB
Reactivity Mouse,Rat
Application WB, IHC-P, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:1000
ICC/IF: 1:100-1:200
FC: 1:200-1:500
Calculated MW 37 kDa
Observed MW 44,27,24 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR18146
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of Cathepsin B in Rat Brain,C6,3T3 cell lysates using db12432(1:1000 diluted).
Immunofluorescent analysis of Raw264.7 cells using db12432

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