Cathepsin B (DGR18146) Rabbit mAb
Product Name :
Cathepsin B (DGR18146) Rabbit mAb
Cat.No.:
db12432
Synonyms :
CB
Reactivity :
Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]
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Immunogen
Recombinant protein of mouse Cathepsin B
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Gene ID
13030
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Swiss Prot
P10605
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Synonyms
CB
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Reactivity
Mouse,Rat
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Application
WB, IHC-P, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000
ICC/IF: 1:100-1:200
FC: 1:200-1:500
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Calculated MW
37 kDa
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Observed MW
44,27,24 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR18146
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot detection of Cathepsin B in Rat Brain,C6,3T3 cell lysates using Cathepsin B antibody(1:1000 diluted).
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Immunofluorescent analysis of Raw264.7 cells using db12432 antibody (green), and DAPI (blue).
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.