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Caldesmon (DGR11987) Rabbit mAb (AF647)
db12512-DL647
Datasheet
Conjugation/Formulation：AF647
- Background This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human Caldesmon
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Gene ID
800
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Swiss Prot
Q05682
- Synonyms CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22
- Reactivity Human, Mouse, Rat
- Application IHC-P, ICC/IF, FC
- Recommended dilution ICC/IF: 1:200
- Calculated MW 93 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11987
- Isotype IgG
- Purity Affinity Purification
- Conjugation AF647
- Concentration 1 mg/mL
- Storage/Stability Store at -20°C. Avoid exposure to light. Supplied in PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. Stable for 12 months from date of receipt.
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Immunofluorescence analysis of HeLa cells labelling Caldesmon with db12512-DL647.
The cells were fixed with cold 100% methanol (10min, 4℃) and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db12512-DL647 (1:200，shown in red) at room temprature for 1h. Nuclear DNA was labeled in blue with DAPI.
Control: DAPI only.
订购信息
- Package Price (RMB)
- 100μL 2698
- 货期：现货
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For research use only. Not intended for diagnostic.
