MBD3 (DGR12319) Rabbit mAb (PBS Only)
Product Name :
MBD3 (DGR12319) Rabbit mAb (PBS Only)
Cat.No.:
db12550-PBS
Synonyms :
Methyl-CpG-binding protein MBD3
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
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Immunogen
A synthetic peptide of human MBD3
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Gene ID
53615
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Swiss Prot
O95983
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Synonyms
Methyl-CpG-binding protein MBD3
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Reactivity
Human,Mouse,Rat
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Application
WB, ICC/IF, FC, IP
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Calculated MW
33 kDa
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Observed MW
33 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR12319
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from HeLa cells using
db12550 at 1:1000.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.