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BMP4 (DGR15418) Rabbit mAb (PBS Only)
db12985-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]
- Immunogen A synthetic peptide of human BMP4
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Gene ID
652
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Swiss Prot
P12644
- Synonyms ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
- Reactivity Human
- Application WB, IHC-P, ICC/IF, FC, IP
- Calculated MW 47 kDa
- Observed MW 47 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15418
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from K562, HeLa cells using db12985 at 1:1000. -
Western blot analysis of extracts from HepG2 cells using db12985 at 1:5000. -
Immunofluorescent analysis of HepG2 cells using db12985 antibody (green), and DAPI (blue). -
Immunofluorescence analysis of HeLa cells labelling BMP4 with db12985.
The cells were fixed with 4% PFA (10min, RT) followed by treatment with 0.1% Triton X-100 (10min, RT), and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db12985 (1:200) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 (db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.
Control: Secondary antibody only.
订购信息
- Package Price (RMB)
- 10μg 1898
- 100μg 5798
- 货期：现货
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For research use only. Not intended for diagnostic.
