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Spry-2 (DGR34014) Rabbit mAb
db12996
Datasheet
- Background This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human Spry-2
-
Gene ID
10253
-
Swiss Prot
O43597
- Synonyms IGAN3; hSPRY2
- Reactivity Human,Rat
- Application WB, IHC-P, ICC/IF
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:50
ICC/IF: 1:100 - Calculated MW 35 kDa
- Observed MW 35 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR34014
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
