TGF beta Receptor II (DGR33771) Rabbit mAb (PBS Only)
Product Name :
TGF beta Receptor II (DGR33771) Rabbit mAb (PBS Only)
Cat.No.:
db13044-PBS
Synonyms :
AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TBRII; TBR-ii; TGFR-2; TGFbeta-RII
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
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Immunogen
Recombinant protein of human TGF beta Receptor II
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Gene ID
7048
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Swiss Prot
P37173
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Synonyms
AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TBRII; TBR-ii; TGFR-2; TGFbeta-RII
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Reactivity
Human
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Application
ICC/IF, FC
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Recommended dilution
ICC/IF: 1:500-1:1000
FC: 1:20-1:50
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Calculated MW
65 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR33771
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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