mGluR1a单克隆抗体(DGR33493) | 高特异性&高亲和力

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Recombinant DGRmAb^®

mGluR1a (DGR33493) Rabbit mAb (PBS Only)

db13137-PBS

Datasheet

Product Name : mGluR1a (DGR33493) Rabbit mAb (PBS Only)

Cat.No.: db13137-PBS

Synonyms : MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Immunogen A synthetic peptide of human mGluR1a
Gene ID 2911
Swiss Prot Q13255
Synonyms MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85
Reactivity Human,Mouse,Rat
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 132 kDa
Observed MW 125,250 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR33493
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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