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Product Name : mGluR1a (DGR33493) Rabbit mAb
Cat.No.: db13137
Synonyms : MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85
Application：
Reactivity : Human, Mouse, Rat
Host species : Rabbit
Conjugation/Formulation：Un-conjugated
- Background This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Immunogen A synthetic peptide of human mGluR1a
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Gene ID
2911
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Swiss Prot
Q13255
- Synonyms MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85
- Reactivity Human,Mouse,Rat
- Application WB
- Recommended dilution WB: 1:1000-1:5000
- Calculated MW 132 kDa
- Observed MW 125,250 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR33493
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Mouse brain tissue using db13137 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
