Nicotinic Acetylcholine Receptor alpha 4 (DGR31592) Rabbit mAb (PBS Only)
Product Name :
Nicotinic Acetylcholine Receptor alpha 4 (DGR31592) Rabbit mAb (PBS Only)
Cat.No.:
db13160-PBS
Synonyms :
EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
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Immunogen
A synthetic peptide of human Nicotinic Acetylcholine Receptor alpha 4/CHRNA4
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Gene ID
1137
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Swiss Prot
P43681
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Synonyms
EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4
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Reactivity
Human,Mouse,Rat
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Application
WB
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Recommended dilution
WB: 1:2000-1:20000
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Calculated MW
70 kDa
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Observed MW
70 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR31592
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from HeLa, CHO-K1, C6, Ramos cells using
db13160 at 1:1000.
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Western blot analysis of extracts from HepG2, T24, RAW264.7, PC-12 cells using
db13160 at 1:5000.
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Western blot analysis of extracts from 3T3 cells using
db13160 at 1:1000.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.