Product Name : Nicotinic Acetylcholine Receptor alpha 4 (DGR31592) Rabbit mAb
Cat.No.: db13160
Synonyms : EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4
Reactivity : Human, Mouse, Rat
Host species : Rabbit
Conjugation/Formulation：Un-conjugated
- Background This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
- Immunogen A synthetic peptide of human Nicotinic Acetylcholine Receptor alpha 4/CHRNA4
-
Gene ID
1137
-
Swiss Prot
P43681
- Synonyms EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4
- Reactivity Human,Mouse,Rat
- Application WB
- Recommended dilution WB: 1:2000-1:20000
- Calculated MW 70 kDa
- Observed MW 70 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR31592
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
-
Western blot analysis of extracts from HeLa, CHO-K1, C6, Ramos cells using db13160 at 1:1000. -
Western blot analysis of extracts from HepG2, T24, RAW264.7, PC-12 cells using db13160 at 1:5000. -
Western blot analysis of extracts from 3T3 cells using db13160 at 1:1000.
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
