RAS单克隆抗体(DGR13636) | 高特异性&高亲和力

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Recombinant DGRmAb^®

RAS (DGR13636) Rabbit mAb (PBS Only)

db13171-PBS

Datasheet

Product Name : RAS (DGR13636) Rabbit mAb (PBS Only)

Cat.No.: db13171-PBS

Synonyms : NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
Immunogen A synthetic peptide of human RAS
Gene ID 4893
Swiss Prot P01111
Synonyms NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:500-1:2000
ICC/IF: 1:50-1:100
FC: 1:20-1:50
IP: 1:10-1:100
Calculated MW 22 kDa
Observed MW 22 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR13636
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of Ras in Hela,3T3,C6,Rat Brain,MCF7 cell lysates using db13171(1:1000 diluted).
Western blot analysis of extracts from 293 cells using db13171

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