Phospho-gamma H2A.X (Ser139) (DGR18728) Rabbit mAb (AF488)
Product Name :
Phospho-gamma H2A.X (Ser139) (DGR18728) Rabbit mAb (AF488)
Cat.No.:
db13191-DL488
Synonyms :
H2AX; H2A.X; H2A/X
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:AF488
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human gamma H2A.X
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Gene ID
3014
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Swiss Prot
P16104
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Synonyms
H2AX; H2A.X; H2A/X
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P, ICC/IF, IP
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Recommended dilution
ICC/IF: 1:100
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Calculated MW
15 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR18728
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
AF488
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Concentration
1 mg/mL
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Storage/Stability
Store at -20°C. Avoid exposure to light. Supplied in PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μL
2698
- 货期:现货
For research use only. Not intended for diagnostic.