Phospho-gamma H2A.X (Ser139) (DGR18728) Rabbit mAb (PBS Only)
Product Name :
Phospho-gamma H2A.X (Ser139) (DGR18728) Rabbit mAb (PBS Only)
Cat.No.:
db13191-PBS
Synonyms :
H2AX; H2A.X; H2A/X
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human gamma H2A.X
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Gene ID
3014
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Swiss Prot
P16104
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Synonyms
H2AX; H2A.X; H2A/X
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P, ICC/IF, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:1000
ICC/IF: 1:100-1:200
IP: 1:20-1:50
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Calculated MW
15 kDa
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Observed MW
15 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR18728
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of gamma H2A.X (Phospho-Ser139) in Jurkat,THP-1,C6,3T3 cell lysates using
db13191(1:1000 diluted).
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.