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Conjugation/Formulation：Un-conjugated
- Background This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr1349 of human Met
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Gene ID
4233
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Swiss Prot
P08581
- Synonyms HGFR; AUTS9; RCCP2; c-Met; DFNB97
- Reactivity Human
- Application WB, IHC-P, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:50-1:100
IP: 1:20-1:200 - Calculated MW 156 kDa
- Observed MW 170140 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR31666
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Met (c-Met) (phospho-Tyr1349) in Hela,A549 cell lysates using Met (c-Met) (phospho-Tyr1349) antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
