CDC42单克隆抗体(DGR15342) | 高特异性&高亲和力

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Recombinant DGRmAb^®

CDC42 (DGR15342) Rabbit mAb (PBS Only)

db14118-PBS

Datasheet

Product Name : CDC42 (DGR15342) Rabbit mAb (PBS Only)

Cat.No.: db14118-PBS

Synonyms : TKS; G25K; CDC42Hs

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Immunogen Recombinant protein of human CDC42
Gene ID 998
Swiss Prot P60953
Synonyms TKS; G25K; CDC42Hs
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:2000-1:20000
IHC-P: 1:100-1:200
ICC/IF: 1:200-1:500
FC: 1:100-1:200
IP: 1:20-1:50
Calculated MW 21 kDa
Observed MW 21 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR15342
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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