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Recombinant DGRmAb®
GCLC (DGR20538) Rabbit mAb (PBS Only)
db14254-PBS
Datasheet

Product Name : GCLC (DGR20538) Rabbit mAb (PBS Only)

Cat.No.: db14254-PBS

Synonyms : GCL; GCS; GLCL; GLCLC

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation：PBS Only

Un-conjugated PBS Only
  • Background Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
  • Immunogen A synthetic peptide of human GCLC
  • Gene ID 2729
  • Swiss Prot P48506
  • Synonyms GCL; GCS; GLCL; GLCLC
  • Reactivity Human,Mouse,Rat
  • Application WB, IP
  • Recommended dilution WB: 1:2000-1:20000
    IP: 1:20
  • Calculated MW 73 kDa
  • Observed MW 73 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR20538
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/ml
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
  • Western blot detection of GCLC in C6 cell lysates using db14254(1:1000 diluted).
  • Western blot analysis of extracts from Rat kidney tissue using db14254
订购信息
  • Package Price (RMB)
  • 100μg 5798
  • 货期：现货
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For research use only. Not intended for diagnostic.