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Conjugation/Formulation：Un-conjugated
- Background Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
- Immunogen A synthetic peptide of human GCLC
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Gene ID
2729
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Swiss Prot
P48506
- Synonyms GCL; GCS; GLCL; GLCLC
- Reactivity Human,Mouse,Rat
- Application WB, IP
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Recommended dilution
WB: 1:2000-1:20000
IP: 1:20 - Calculated MW 73 kDa
- Observed MW 73 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR20538
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of GCLC in C6 cell lysates using GCLC antibody(1:1000 diluted). -
Western blot analysis of extracts from Rat kidney tissue using db14254 at 1:2000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
