CD130单克隆抗体(DGR20036) | 高特异性&高亲和力

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Recombinant DGRmAb^®

CD130 (DGR20036) Rabbit mAb (PBS Only)

db14373-PBS

Datasheet

Product Name : CD130 (DGR20036) Rabbit mAb (PBS Only)

Cat.No.: db14373-PBS

Synonyms : CD130; GP130; CDW130; IL-6RB

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
Immunogen Recombinant protein of human CD130
Gene ID 3572
Swiss Prot P40189
Synonyms CD130; GP130; CDW130; IL-6RB
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 104 kDa
Observed MW 130 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR20036
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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