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Product Name : CD130 (DGR20036) Rabbit mAb
Cat.No.: db14373
Synonyms : CD130; GP130; CDW130; IL-6RB
Application：
Reactivity : Human
Host species : Rabbit
Conjugation/Formulation：Un-conjugated
- Background The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
- Immunogen Recombinant protein of human CD130
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Gene ID
3572
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Swiss Prot
P40189
- Synonyms CD130; GP130; CDW130; IL-6RB
- Reactivity Human
- Application WB
- Recommended dilution WB: 1:1000
- Calculated MW 104 kDa
- Observed MW 130 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR20036
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HeLa cells using db14373 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
