Estrogen Receptor alpha (DGR20010) Rabbit mAb (PBS Only)
Product Name :
Estrogen Receptor alpha (DGR20010) Rabbit mAb (PBS Only)
Cat.No.:
db14385-PBS
Synonyms :
ER; ESR; Era; ESRA; ESTRR; NR3A1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
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Immunogen
A synthetic peptide of human Estrogen Receptor alpha
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Gene ID
2099
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Swiss Prot
P03372
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Synonyms
ER; ESR; Era; ESRA; ESTRR; NR3A1
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Reactivity
Human
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Application
WB, IHC-P
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000
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Calculated MW
66 kDa
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Observed MW
66 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR20010
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from MCF-7 cells using
db14385
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.