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Estrogen Receptor alpha (DGR20010) Rabbit mAb

Product Name : Estrogen Receptor alpha (DGR20010) Rabbit mAb

Cat.No.: db14385

Synonyms : ER; ESR; Era; ESRA; ESTRR; NR3A1

Application:

Reactivity : Human

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
  • Immunogen A synthetic peptide of human Estrogen Receptor alpha
  • Gene ID 2099
  • Swiss Prot P03372
  • Synonyms ER; ESR; Era; ESRA; ESTRR; NR3A1
  • Reactivity Human
  • Application WB, IHC-P
  • Recommended dilution WB: 1:1000
    IHC-P: 1:200-1:1000
  • Calculated MW 66 kDa
  • Observed MW 66 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR20010
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from MCF-7 cells using db14385 at 1:1000.
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.