Estrogen Receptor alpha (DGR20010) Rabbit mAb
Product Name :
Estrogen Receptor alpha (DGR20010) Rabbit mAb
Cat.No.:
db14385
Synonyms :
ER; ESR; Era; ESRA; ESTRR; NR3A1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
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Immunogen
A synthetic peptide of human Estrogen Receptor alpha
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Gene ID
2099
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Swiss Prot
P03372
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Synonyms
ER; ESR; Era; ESRA; ESTRR; NR3A1
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Reactivity
Human
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Application
WB, IHC-P
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000
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Calculated MW
66 kDa
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Observed MW
66 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR20010
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from MCF-7 cells using db14385 at 1:1000.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.