MDA5 (DGR16158) Rabbit mAb (PBS Only)
Product Name :
MDA5 (DGR16158) Rabbit mAb (PBS Only)
Cat.No.:
db14892-PBS
Synonyms :
AGS7; Hlcd; MDA5; MDA-5; RLR-2; IDDM19; SGMRT1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012]
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Immunogen
A synthetic peptide of human MDA5
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Gene ID
64135
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Swiss Prot
Q9BYX4
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Synonyms
AGS7; Hlcd; MDA5; MDA-5; RLR-2; IDDM19; SGMRT1
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000-1:5000
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Calculated MW
117 kDa
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Observed MW
135 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR16158
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from HeLa cells using
db14892
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.