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Product Name : MDA5 (DGR16158) Rabbit mAb
Cat.No.: db14892
Synonyms : AGS7; Hlcd; MDA5; MDA-5; RLR-2; IDDM19; SGMRT1
Application：
Reactivity : Human
Host species : Rabbit
Conjugation/Formulation：Un-conjugated
- Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012]
- Immunogen A synthetic peptide of human MDA5
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Gene ID
64135
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Swiss Prot
Q9BYX4
- Synonyms AGS7; Hlcd; MDA5; MDA-5; RLR-2; IDDM19; SGMRT1
- Reactivity Human
- Application WB
- Recommended dilution WB: 1:1000-1:5000
- Calculated MW 117 kDa
- Observed MW 135 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16158
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HeLa cells using db14892 at 1:3000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
