SLAMF7 (DGR14979) Rabbit mAb (PBS Only)
Product Name :
SLAMF7 (DGR14979) Rabbit mAb (PBS Only)
Cat.No.:
db15176-PBS
Synonyms :
19A; CS1; CD319; CRACC
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536).
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Immunogen
Recombinant protein of human SLAMF7
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Gene ID
57823
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Swiss Prot
Q9NQ25
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Synonyms
19A; CS1; CD319; CRACC
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Reactivity
Human
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Application
WB, IHC-P, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:2000
IP: 1:20-1:50
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Calculated MW
37 kDa
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Observed MW
37 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR14979
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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