SLAMF7单克隆抗体(DGR14979) | 高特异性&高亲和力

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Recombinant DGRmAb^®

SLAMF7 (DGR14979) Rabbit mAb

db15176

年底大促

Datasheet

Product Name : SLAMF7 (DGR14979) Rabbit mAb

Cat.No.: db15176

Synonyms : 19A; CS1; CD319; CRACC

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536).
Immunogen Recombinant protein of human SLAMF7
Gene ID 57823
Swiss Prot Q9NQ25
Synonyms 19A; CS1; CD319; CRACC
Reactivity Human
Application WB, IHC-P, IP
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:2000
IP: 1:20-1:50
Calculated MW 37 kDa
Observed MW 37 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR14979
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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