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IGF2BP2 (DGR11373) Rabbit mAb

Product Name : IGF2BP2 (DGR11373) Rabbit mAb

Cat.No.: db16009

Synonyms : IMP2; IMP-2; VICKZ2

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]
  • Immunogen A synthetic peptide of human IGF2BP2
  • Gene ID 10644
  • Swiss Prot Q9Y6M1
  • Synonyms IMP2; IMP-2; VICKZ2
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P, ICC/IF
  • Recommended dilution WB: 1:1000-1:5000
    IHC-P: 1:100-1:200
    ICC/IF: 1:100-1:200
  • Calculated MW 66 kDa
  • Observed MW 66 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR11373
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from 293T cells using db16009 at 1:1000.
  • Immunofluorescence analysis of HepG2 cells labelling IGF2BP2 with db16009.

    The cells were fixed with 4% PFA (10min, RT) followed by treatment with 0.1% Triton X-100 (10min, RT), and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db16009 (1:100) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 (db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.

    Control: Secondary antibody only.
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.