Bcl-XL (DGR11336) Rabbit mAb (PBS Only)
Product Name :
Bcl-XL (DGR11336) Rabbit mAb (PBS Only)
Cat.No.:
db16019-PBS
Synonyms :
BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
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Immunogen
A synthetic peptide of human Bcl-XL
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Gene ID
598
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Swiss Prot
Q07817
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Synonyms
BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P, ICC/IF, FC, IP
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Calculated MW
26 kDa
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Observed MW
30 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR11336
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
7858
- 货期：现货
For research use only. Not intended for diagnostic.
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