DDB2 (DGR36085) Rabbit mAb (PBS Only) - diagbio | 戴格生物

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Recombinant DGRmAb^®

DDB2 (DGR36085) Rabbit mAb (PBS Only)

db16320-PBS

Datasheet

Product Name : DDB2 (DGR36085) Rabbit mAb (PBS Only)

Cat.No.: db16320-PBS

Synonyms : XPE; DDBB; UV-DDB2

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Immunogen A synthetic peptide of human DDB2
Gene ID 1643
Swiss Prot Q92466
Synonyms XPE; DDBB; UV-DDB2
Reactivity Human
Application WB, IHC-P
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:500-1:2000
Calculated MW 48 kDa
Observed MW 48 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36085
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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